CAS: | 950912-80-8 |
分子式: | C19H22Cl2FN5 |
分子量: | 410.32 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 7.7 nM (CKIε), 14 nM (CKIδ), 150 nM (EGFR), 190 nM (SAPK2A/p38)[1], 17 nM (Wnt/β-catenin)[2] |
描述: | PF-670462 is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ), with IC50 of 7.7 nM and 14 nM, respectively. |