KetorolacD5是Ketorolac的氘代物。Ketorolac是一种非甾体抗炎剂，为非选择性的COX 抑制剂，对COX-1和COX-2的IC50s 值分别为20nM和120nM。
| Cas No. | 1215767-66-0 |
| 别名 | 酮咯酸D5 |
| Canonical SMILES | O=C(C1C2=CC=C(C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O)N2CC1)O |
| 分子式 | C15H8D5NO3 |
| 分子量 | 260.3 |
| 溶解度 | Chloroform: slightly soluble,Methanol: slightly soluble |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ketorolac D5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM for COX-1 and 120 nM for COX-2[1]. [1]. Waterbury LD, et al. Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium. Curr Med Res Opin. 2006 Jun;22(6):1133-40. |
