Unoprostone 是一种前列腺素 F2α 类似物 (PGA),可激活 BK 通道以减少氧化应激和光诱导的视网膜细胞死亡和吞噬功能障碍。
Cas No. | 120373-36-6 |
别名 | 乌诺前列酮 |
Canonical SMILES | O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCCCCCC)=O)[C@H](O)C1 |
分子式 | C22H38O5 |
分子量 | 382.5 |
溶解度 | DMF: 25 mg/ml,DMSO: 17 mg/ml,Ethanol: 12 mg/ml,PBS (7.2): 90 µ g/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Unoprostone is an analog of PGF2α with a 13,14-dihydro-15-keto modification and a two-carbon extension of the aliphatic lower side chain. The isopropyl ester of unoprostone ( (Rescula) has been approved for clinical use as an ocular hypotensive drug. |