Zamicastat(BIA 5-1058)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
| CAS: | 1080028-80-3 |
| 分子式: | C21H21F2N3OS |
| 分子量: | 401.47 |
| 纯度: | >98% |
| 溶解性: | DMSO |
| 存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域: | Cancer; Cardiovascular Disease |
| Target: | Dopamine β-hydroxylase (DBH); IC50: 73.8 μM (P-gp), 17.0 μM (BCRP) |
| 描述: | Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor, and a dual P-gp and BCRP inhibitor, which crosses the blood-brain barrier (BBB). |