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H-Nle-OH
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
H-Nle-OH图片
CAS NO:327-57-1
包装与价格：
包装价格(元)
5g询价
25g询价

H-Nle-OH ((S)-2-Aminohexanoic acid) 是亮氨酸的异构体，特异性影响骨骼肌中的蛋白质合成，具有抗病毒活性。
Cas No.327-57-1
别名L-正亮氨酸,(S)-2-Aminohexanoic acid; (S)-Norleucine
化学名(2S)-2-aminohexanoic acid
Canonical SMILESCCCCC(C(=O)O)N
分子式C6H13NO2
分子量131.2
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

L-Norleucine is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

L-Norleucine is an isomer of leucine, specifically affecting protein synthesis in skeletal muscle[1]. L-Norleucine has antiviral activity. L-Norleucine interacts with hnRNPA2/B1 protein to suppresses the expressions of Twist1 and Snail, two inhibitors of E-cadherin, and promotes the expression of E-cadherin, resulting in the inhibition of tumor metastasis[2].

References:
[1]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.
[2]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.

 
 
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