Carboxyatractyloside dipotassium 是一种有毒性的天然产物,为 ADP/ATP 载体蛋白 (ADP/ATP carrier) 抑制剂,抑制线粒体 ADP/ATP 的转运。
Cas No. | 33286-30-5 |
别名 | 羧基苍术苷,Gummiferin dipotassium |
Canonical SMILES | C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])C(C(O[K])=O)(C(O[K])=O)C[C@@H](O[C@@H]5[C@H]([C@@H]([C@H]([C@H](CO)O5)OS(=O)(O)=O)OS(=O)(O)=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H] |
分子式 | C31H44K2O18S2 |
分子量 | 847 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Carboxyatractyloside dipotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport[1]. [1]. Pebay-Peyroula E, et al. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature. 2003 Nov 6;426(6962):39-44. |