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Carmoisine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Carmoisine图片
CAS NO:3567-69-9
包装:100mg
市场价:900元

Carmoisine(Azorubine)是一种偶氮染料,可用作食品添加剂。
Cas No.3567-69-9
别名偶氮玉红; Azorubine; Acid Red 14; E122
Canonical SMILESO=S(C1=C2C=CC=CC2=C(O)C(/N=N/C3=C4C=CC=CC4=C(S(=O)(O[Na])=O)C=C3)=C1)(O[Na])=O
分子式C20H12N2Na2O7S2
分子量502.43
溶解度DMSO: 50 mg/mL (99.52 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2].

Carmoisine augments the in vitro synthesis of leukotriene B4 (LTB4) and F2-isoprostanes from blood neutrophils. Carmoisine increases the formation of F2-isoprostanes from blood neutrophils at all tested concentrations[2].

Carmoisine (49.3-493 mg/kg; oral administration; for 42 days; male Wistar rats) treatment increases MAPK8 expression at remarkably low and high concentrations, the expression of NFκB and GADD45α does not change[1]. Animal Model: Male Wistar rats (120-300 g)[1]

[1]. B Raposa, et al. Food additives: Sodium benzoate, potassium sorbate, azorubine, and tartrazine modify the expression of NFκB, GADD45α, and MAPK8 genes. Physiol Int. 2016 Sep;103(3):334-343. [2]. Latasha Leo, et al. Occurrence of azo food dyes and their effects on cellular inflammatory responses. Nutrition. 2018 Feb;46:36-40.

 
 
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