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Chebulic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Chebulic acid图片
CAS NO:23725-05-5

Chebulic acid 是一种从 Terminalia chebula 中分离出的酚羧酸化合物,具有很强的抗氧化活性,它打破了由晚期糖基化终产物 (AGEs) 诱导的蛋白质交联,抑制了 (AGEs) 的形成。Chebulic acid 对控制代谢参数升高、氧化应激和肾损害有效,支持其在糖尿病肾病中的有益作用。
Cas No.23725-05-5
别名诃子次酸
Canonical SMILESO=C(O)[C@H]([C@@H](C1=C(O)C(O)=C(O)C=C12)[C@@H](C(O)=O)OC2=O)CC(O)=O
分子式C14H12O11
分子量356.24
溶解度DMSO: 260 mg/mL (729.85 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity, which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress and renal damage, supporting its beneficial effect in diabetic nephropathy[1][2].

[1]. Lee KW, et al. Protective effects of chebulic acid on alveolar epithelial damage induced by urban particulate matter. BMC Complement Altern Med. 2017 Jul 19;17(1):373. [2]. Silawat N, et al. Chebulic acid attenuates ischemia reperfusion induced biochemical alteration in diabetic rats. Pharm Biol. 2013 Jan;51(1):23-9.

 
 
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