Camellianin A 是 A. nitida 叶中主要的黄酮类化合物，具有抗癌活性和抗血管紧张素转换酶 (ACE) 活性。Camellianin A 能抑制人 Hep G2 和 MCF-7 细胞的增殖，诱导细胞 G0/G1 期停滞。
| Cas No. | 109232-77-1 |
| 别名 | 山茶黄酮苷 A |
| Canonical SMILES | O[C@H]([C@@H](O)[C@@H]1O[C@@](O[C@@H](C)[C@H](O)[C@H]2O)([H])[C@@H]2O)[C@@H](O[C@@H]1COC(C)=O)OC3=C(C4=O)C(OC(C5=CC=C(O)C=C5)=C4)=CC(O)=C3 |
| 分子式 | C29H32O15 |
| 分子量 | 620.56 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Camellianin A, the main flavonoid in A. nitida leaves, displays anticancer activity and angiotensin converting enzyme (ACE)-inhibitory activity. Camellianin A inhibits the proliferation of the human Hep G2 and MCF-7 cell lines and induces the significant increase of the G0/G1 cell population[1][2]. [1]. Gao H, et al. Anti-proliferative effect of camellianin A in Adinandra nitida leaves and its apoptotic induction in human Hep G2 and MCF-7 cells. Molecules. 2010 May 28;15(6):3878-86.
[2]. Liu B, et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm Biol. 2010 Dec;48(12):1432-8. |
