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(E)-Flavokawain A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(E)-Flavokawain A图片
CAS NO:37951-13-6

(E)-Flavokawain A 是从卡瓦胡椒中提取的查尔酮,具有抗癌作用。(E)-Flavokawain A 通过介入 bax 蛋白依赖和线粒体依赖的凋亡通路,诱导膀胱癌细胞凋亡,抑制小鼠肿瘤生长。
Cas No.37951-13-6
别名卡瓦胡椒素A
Canonical SMILESO=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(OC)C=C2.[E]
分子式C18H18O5
分子量314.33
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(E)-Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. (E)-Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].

[1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.

 
 
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