selective inhibitor of PARP1/PARP2
Cas No. | 1038915-75-1 |
化学名 | 2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carbimidic acid |
Canonical SMILES | N=C(O)C1=CC=CC(C1=N2)=CN2C3=CC=C(C4CCCNC4)C=C3 |
分子式 | C19H20N4O |
分子量 | 320.39 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | MK-4827 racemate (Niraparib racemate) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM; >330-fold selective against PARP3, V-PARP and Tank1. |