(-)-BAY-1251152 ((-)-BAY-1251152) 是具有旋转 (-) 的 BAY-1251152 的对映体。 BAY-1251152 是一种有效且高度选择性的 PTEF/CDK9 抑制剂。
| Cas No. | 1610358-59-2 |
| 别名 | (-)-BAY-1251152; (-)-VIP152 |
| Canonical SMILES | N=S(CC1=CC(NC2=NC=C(F)C(C3=CC=C(F)C=C3OC)=C2)=NC=C1)(C)=O.[Rotation(-)] |
| 分子式 | C19H18F2N4O2S |
| 分子量 | 404.43 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (-)-BAY-1251152 is an enanthiomer of BAY-1251152 with rotation (-). BAY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. [1]. Luecking, et al. Identification of potent and highly selective PTEFb inhibitor BAY 1251152 for the treatment of cancer: from p.o. to i.v. application via scaffold hops. AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 984. doi:10.1158/1538-7445.AM2017-984 |
