| CAS NO: | 942936-75-6 |
Phen-DC3是一个G4特异性配体，可以抑制解旋酶FANCJ和DinG且IC50s值分别为65±6和50±10nM。
| Cas No. | 942936-75-6 |
| Canonical SMILES | C[N+]1=C2C=CC=CC2=CC(NC(C3=CC=C4C=CC5=CC=C(C(NC6=C[N+](C)=C7C=CC=CC7=C6)=O)N=C5C4=N3)=O)=C1 |
| 分子式 | C34H26N6O2 |
| 分子量 | 550.61 |
| 溶解度 | DMSO : ≥ 34 mg/mL (61.75 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively. [1]. Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29. |
| 维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024 |