TyK2 inhibitor 2
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CAS: | 2098466-94-3 |
分子式: | C16H18N6O |
分子量: | 310.35 |
纯度: | >98% |
溶解性: | DMSO : ≥ 25 mg/mL (80.55 mM) |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Inflammation/Immunology |
Target: | Tyk2 JH2:7 nM (IC50);PDE4:62 nM (IC50) |
描述: | TyK2 inhibitor 2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 μM and 0.05 μM for TYK2 JH2, IL-23 and IFNα, respectively. TyK2 inhibitor 2 also inhibits phosphodiestera |