Surfactin 是一种有效的环状脂肽生物表面活性剂,由四种异构体(Surfactin A、B、C 和 D)组成,可介导单价和二价阳离子(如钙)穿过脂质双层膜的通量。
Cas No. | 24730-31-2 |
别名 | 表面活性素 |
Canonical SMILES | OC(C[C@H](N1)C(N[C@](C(N[C@H](C(OC(CC(N[C@@H](CCC(O)=O)C(N[C@](CC(C)C)([H])C(N[C@H](CC(C)C)C(N[C@@H](C(C)C)C1=O)=O)=O)=O)=O)CCCCCCCCCC(C)C)=O)CC(C)C)=O)([H])CC(C)C)=O)=O |
分子式 | C53H93N7O13 |
分子量 | 1036.34 |
溶解度 | DMSO: 50 mg/mL (48.25 mM); Water: 31.25 mg/mL (30.15 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects[1][2]. Surfactin also has antiviral activity against a variety of enveloped viruses[3]. [1]. Liu J, et al. Sensitization of avian pathogenic Escherichia coli to amoxicillin in vitro and in vivo in the presence of surfactin. PLoS One. 2019 Sep 12;14(9):e0222413.
[2]. Wei-Chuan Chena, et al. Applications of a lipopeptide biosurfactant, surfactin, produced by microorganisms. Biochemical Engineering Journal. 103 (2015) 158-169.
[3]. Vollenbroich D, et al. Mechanism of inactivation of enveloped viruses by the biosurfactant surfactin from Bacillus subtilis. Biologicals. 1997 Sep;25(3):289-97. |