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TH 1217
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TH 1217图片
CAS NO:1862212-48-3
包装:5mg
市场价:1602元

TH 1217 (ZINC1775962367) 是一种有效的选择性 dCTPase pyrophosphatase 1 (dCTPase) 抑制剂,IC50 为 47 nM。
Cas No.1862212-48-3
别名ZINC1775962367
Canonical SMILESCC1=NC2=C([N+]([O-])=O)C(Cl)=C(C=C2N1CC3=CC=C([B-]45OC(C[N+](CC(O5)=O)4C)=O)C=C3)Cl
分子式C20H17BCl2N4O6
分子量491.09
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Potent dCTPase pyrophosphatase 1 inhibitor (IC50 = 47 nM). TH 1217 is not stable in aqueous solution. It is recommended that fresh samples are prepared and used immediately.

Llona-Minguez et al (2016) Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1. J.Med.Chem. 59 1140 PMID:26771665

 
 
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