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AZD 2066
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AZD 2066图片
CAS NO:934282-55-0

AZD 2066 是一种选择性、可口服、能透过血脑屏障的 mGluR5 拮抗剂,具有镇痛作用。
Cas No.934282-55-0
Canonical SMILESCN1C(C2=CC=NC=C2)=NN=C1O[C@@H](C3=NOC(C4=CC(Cl)=CC=C4)=C3)C
分子式C19H16ClN5O2
分子量381.82
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].

[1]. Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.

 
 
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