VU0364770 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS: | 1414842-70-8 |
分子式: | C12H10Cl2N2O |
分子量: | 269.13 |
纯度: | >98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Neurological Disease |
Target: | Rat mGlu4; 290 nM (EC50); Human mGlu4; 1.1 μM (EC50); mGlu6; 6.8 μM (EC50); mGlu5; 17.9 μM (EC50) |
描述: | VU0364770 hydrochloride is a selective and potent positive allosteric modulator (PAM) of mGlu4, and exhibits EC50s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively. |