Cyclopentolate (DL-Cyclopentolate) hydrochloride 是一种阿托品样毒蕈碱受体拮抗剂，pKB 值为 7.8（在睫状环肌上）。
| Cas No. | 5870-29-1 |
| 别名 | 盐酸环喷托酯,DL-Cyclopentolate hydrochloride |
| Canonical SMILES | O=C(OCCN(C)C)C(C1(O)CCCC1)C2=CC=CC=C2.Cl |
| 分子式 | C17H25NO3•HCl |
| 分子量 | 327.9 |
| 溶解度 | DMSO: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cyclopentolate is an antagonist of muscarinic acetylcholine receptors (Kis = 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively). It inhibits carbachol-induced contraction of isolated human iris sphincter, circular ciliary muscle, and longitudinal ciliary muscle (Kbs = 7.9, 15.8, and 12.5 nM, respectively). Formulations containing cyclopentolate have been used to induce pupil dilation and to prevent the eye from accommodating for near vision. |
