| 产品名称： | 瑞格非尼盐酸盐 |
| CAS： | 835621-07-3 |
| 分子式： | C21H16Cl2F4N4O3 |
| 分子量： | 519.28 |
| 纯度： | >98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Cancer |
| Target： | VEGFR1, 13 nM (IC50); VEGFR2, 4.2 nM (IC50); VEGFR3, 46 nM (IC50); PDGFRβ, 22 nM (IC50); Braf, 28 nM (IC50); BRafV600E, 19 nM (IC50); Raf-1, 2.5 nM (IC50) |
| 描述： | Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively. |
