产品名称: | 甲苯磺酸索拉非尼 |
CAS: | 475207-59-1 |
分子式: | C28H24ClF3N4O6S |
分子量: | 637.03 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
Target: | IC50: 6 nM (Raf-1), 20 nM (VEGFR-3), 22 nM (BRAF), 57 nM (PDGFR-β), 58 nM (Flt3), 68 nM (c-KIT), 90 nM (VEGFR-2)[1] |
描述: | Sorafenib tosylate is a potent multikinase inhibitor, with IC50 of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively. |