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γ-Glu-Cys(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
γ-Glu-Cys(ammonium salt)图片
包装与价格:
包装价格(元)
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An intermediate in GSH synthesis
Canonical SMILESOC([C@@H](N)CCC(N[C@@H](CS)C(O)=O)=O)=O.[NH4+]
分子式C8H14N2O5S.XNH4
分子量250.3
溶解度PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelatins, the heavy metal detoxifying enzymes in plants.2

1.Anderson, M.E., and Meister, A.Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesisProc. Natl. Acad. Sci. USA80(3)707-711(1983) 2.Grill, E., LÖffler, S., Winnacker, E.-L., et al.Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase)Proc. Natl. Acad. Sci. USA86(18)6838-6842(1989)

 
 
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