PT2977(MK-6482)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
| CAS: | 1672668-24-4 |
| 分子式: | C17H12F3NO4S |
| 分子量: | 383.34 |
| 纯度: | >98% |
| 溶解性: | DMSO |
| 存储: | -20℃, stored under nitrogenIn solvent : -80℃, 6 months; --20℃, 1 month (stored under nitrogen) |
| 研究领域: | Cancer |
| Target: | HIF/HIF Prolyl-Hydroxylase |
| 描述: | PT2977 (MK-6482) is an orally active and selective HIF-2α inhibitor with an IC50 of 9 nM. PT2977, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. |