PF04531083是一种选择性的NaV1.8阻滞剂，能够用于神经性或炎症性疼痛的研究。
| Cas No. | 1079400-07-9 |
| 别名 | N-(6-氨基-5-(2-氯-5-甲氧苯基)吡啶-2-基)-1-甲基-1H-吡唑-5-甲酰胺 |
| Canonical SMILES | ClC1=CC=C(OC)C=C1C2=C(N=C(NC(C3=CC=NN3C)=O)C=C2)N |
| 分子式 | C17H16ClN5O2 |
| 分子量 | 357.79 |
| 溶解度 | DMSO: 125 mg/mL (349.37 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PF 04531083 is a selective NaV1.8 blocker, and used for the research of neuropathic/inflammatory pain. [1]. Bagal SK, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9. |
