Dacisteine (N,S-Diacetyl-L-cysteine) 是一种半胱氨酸衍生物，具有很小的 (NDM-1) 抑制活性，IC50 值为 1000 μM。Dacisteine 可用于治疗血小板聚集引起的心脑血管疾病。
| Cas No. | 18725-37-6 |
| 别名 | 达西司坦,N,S-Diacetyl-L-cysteine |
| Canonical SMILES | CC(SC[C@@H](C(O)=O)NC(C)=O)=O |
| 分子式 | C7H11NO4S |
| 分子量 | 205.23 |
| 溶解度 | DMSO: ≥ 250 mg/mL (1218.15 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC50 value of 1000 μM[1]. Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[2]. [1]. Cui-Gai Bai1, et al. Cysteine and Its Derivatives as New Delhi Metallo-beta-lactamase-1 Inhibitors. Current Enzyme Inhibition, 2015, 11, 46-57
[2]. FanKe, et al.Application of compound of thioether acid structure in preparing anti-platelet aggregation drugs. Patent WO2019007015A1. |
