Rosamultin 是一种从 Potentilla anserina L 分离出的 19 α-羟基型三萜。 Rosamultin 对 HIV-1 Protease 具有抑制作用。 Rosamultin 具有抗氧化和抗凋亡作用，具有治疗 H2O2 引起的氧化应激损伤的潜力。
| Cas No. | 88515-58-6 |
| 别名 | 罗莎白素 |
| Canonical SMILES | OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@H]1OC([C@]23[C@]([C@](O)([C@H](C)CC3)C)([H])C4=CC[C@@]([C@@]5([C@@](C(C)([C@@H](O)[C@H](O)C5)C)([H])CC6)C)([H])[C@]6(C)[C@]4(C)CC2)=O |
| 分子式 | C36H58O10 |
| 分子量 | 650.84 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. Rosamultin has inhibitory effects against HIV-1 protease[1]. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects[2]. [1]. Zhang L, et al. Protective Effect of Rosamultin against H2O2-Induced Oxidative Stress and Apoptosis in H9c2 Cardiomyocytes.Oxid Med Cell Longev. 2018 Jul 16;2018:8415610.
[2]. Park JC, et al. Anti-HIV protease activity from rosa family plant extracts and rosamultin from Rosa rugosa.J Med Food. 2005 Spring;8(1):107-9. |
