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DiIC1(5)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DiIC1(5)图片
CAS NO:36536-22-8
包装与价格:
包装价格(元)
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Cas No.36536-22-8
别名1,1',3,3,3',3'-六甲基吲哚双碳菁碘
Canonical SMILESCC1(C)C2=CC=CC=C2N(C)/C1=C/C=C/C=C/C3=[N+](C)C4=C(C=CC=C4)C3(C)C.[I-]
分子式C27H31N2•I
分子量510.5
溶解度DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DiIC1(5) is a signal-off fluorescent probe for the detection of mitochondrial membrane potential disruption. It accumulates in mitochondria and its fluorescence intensity decreases when the mitochondrial membrane potential is disrupted. DilC1(5) has been used in combination with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry. It has also been used as a quencher for the detection of serine phosphorylation and tyrosine dephosphorylation post-translational modifications (PTMs) in quenching resonance energy transfer (QRET) and mTR-FRET applications. It displays excitation/emission maxima of 659/666 nm, respectively.

 
 
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