CAS NO: | 398507-55-6 |
Cas No. | 398507-55-6 |
别名 | 罗地那非碳酸酯 |
Canonical SMILES | CCCC1=NN(C)C2=C1NC(C3=C(C=CC(S(=O)(N4CCN(CCOC(OCCN5CCN(S(=O)(C6=CC(C(NC7=C8N(C)N=C7CCC)=NC8=O)=C(OCC)C=C6)=O)CC5)=O)CC4)=O)=C3)OCC)=NC2=O |
分子式 | C47H62N12O11S2 |
分子量 | 1035.2 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Lodenafil carbonate, a dimer that acts as a prodrug delivering Lodenafil in vivo, is an orally active phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED)[1][2]. PDE5 [1]. Glina S, et al. Efficacy and tolerability of lodenafil carbonate for oral therapy in erectile dysfunction: a phase II clinical trial. J Sex Med. 2009 Feb;6(2):553-7. [2]. Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591(1-3):189-95. |
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