Dehydrocorydaline nitrate 从 Corydalis edulis Maxim 中分离出来的，具有抗疟疾作用。Dehydrocorydaline nitrate 显示出强大的抗疟疾作用，并具低细胞毒性 (细胞生存力>90％)， P. falciparum 3D7 strain (IC50=38 nM)。
| Cas No. | 13005-09-9 |
| 别名 | 硝酸脱氢紫堇碱; 13-Methylpalmatine nitrate |
| Canonical SMILES | O=N([O-])=O.CC1=C(C=CC(OC)=C2OC)C2=C[N+]3=C1C4=CC(OC)=C(OC)C=C4CC3 |
| 分子式 | C22H24N2O7 |
| 分子量 | 428.44 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dehydrocorydaline nitrate is isolated from Corydalis edulis Maxim with anti-malarial effects. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability >90%) using P. falciparum 3D7 strain[1]. [1]. Nonaka M, et al. Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts. Malar J. 2018 Jun 25;17(1):244. doi: 10.1186/s12936-018-2392-4. |
