CDK inhibitor II 是一种有效且特异性的 CDK9 抑制剂，IC50<8 nM，取自参考文献 1，实施例 4。
| Cas No. | 1269815-17-9 |
| 别名 | CDK inhibitorII |
| 化学名 | (3R)-N-[5-chloro-4-(5-fluoro-2-methoxyphenyl)pyridin-2-yl]piperidine-3-carboxamide |
| Canonical SMILES | COC1=C(C=C(C=C1)F)C2=CC(=NC=C2Cl)NC(=O)C3CCCNC3 |
| 分子式 | C18H19ClFN3O2 |
| 分子量 | 363.82 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CDK-IN-2 is a potent and specific CDK9 inhibitor with IC50 of<8 nM, extracted from reference 1, example 4.IC50 Value:<8 nM [1]Target: CDK9In vitro:In vivo: References:
[1]. Keith B Pfister, et al. Heteroaryl compounds as kinase inhibitors. 2011, WO2011026917A1. |
