JWH 133

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JWH 133

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

259869-55-1

包装与价格：

包装	价格(元)
5mg (solution)	询价
10mg (solution)	询价
25mg (solution)	询价

化学性质

Physical Appearance	A solution in methyl acetate. To change the solvent, simply evaporate the acetate containing under a gentle stream of nitrogen and immediately add the solvent of choice.
Storage	Store at -20°C
M.Wt	312.49
Cas No.	259869-55-1
Formula	C₂₂H₃₂O
Solubility	Soluble in DMSO
Chemical Name	(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene
Canonical SMILES	CCCC(C)(C1=CC2=C([C@H]3[C@@H](CC=C(C3)C)C(C)(O2)C)C=C1)C
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

JWH 133 is a synthetic cannabinoid (CB) with Ki values of 3.4 nM and 677 nM for the peripheral CB2 receptor and central CB1 receptor, respectively[1].

JWH 133 inhibits tumor growth in mice, promoting apoptosis and destroying angiogenesis[2]. JWH 133 also inhibits inflammation of experimental colitis and pancreatitis in mice and in vitro models[3].

References：

[1]. Huffman J W, Liddle J, Yu S, et al. 3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry, 1999, 7: 2905-2914.

[2]. Casanova M L, Blázquez C, Martínez-Palacio J, et al. Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. Journal of Clinical Investigation, 2003, 111(1): 43-50.

[3]. Kimball E S, Schneider C R, Wallace N H, et al. Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium. American Journal of Physiology and Gastrointestinal Liver Physiology, 2006, 291(2): G364-G371.