PF-4840154 是一种有效的、选择性的大鼠和人 TrpA1 通道激动剂，EC50 分别为 97 和 23 nM。
| Cas No. | 1332708-14-1 |
| Canonical SMILES | O=C(C1=CN=C(N2CCN(CC3COCCC3)CC2)N=C1NCC(C)C)NCC4=CC=CC=C4 |
| 分子式 | C26H38N6O2 |
| 分子量 | 466.62 |
| 溶解度 | DMSO : 50 mg/mL (107.15 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC50s of 97 and 23 nM, respectively. References:
[1]. Ryckmans T, et al. Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4857-4859. |
