Basmisanil (RG1662) 是一种高度选择性的口服活性α亚基，含有 GABAA 受体 (GABAAα5) 负变构调节剂 (NAM)。
| Cas No. | 1159600-41-5 |
| 别名 | 巴米沙尼,RG1662; RO5186582 |
| Canonical SMILES | O=C(N1CCS(CC1)(=O)=O)C2=CC=C(OCC3=C(C)ON=C3C4=CC=C(F)C=C4)N=C2 |
| 分子式 | C21H20FN3O5S |
| 分子量 | 445.46 |
| 溶解度 | DMSO : ≥ 32 mg/mL (71.84 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Basmisanil is a highly selective GABAAα5 negative allosteric modulator. References:
[1]. Myers JF, et al. Quantification of [11C]Ro15-4513 GABAAα5 specific binding and regional selectivity in humans. J Cereb Blood Flow Metab. 2016 Jul 27. |
