PD-1-IN-17是一种有效的程序性细胞死亡-1(PD-1)抑制剂，详细信息请参考专利文献WO2015033301A1中的化合物12，浓度为100nM时抑制92%脾细胞增殖。
| Cas No. | 1673560-66-1 |
| Canonical SMILES | OC[C@@H](C(O)=O)NC(N[C@H](C1=NN=C([C@@H](N)[C@H](O)C)O1)CCC(N)=O)=O |
| 分子式 | C13H22N6O7 |
| 分子量 | 374.35 |
| 溶解度 | DMSO : 125 mg/mL (333.91 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PD-1-IN-17 is a programmed cell death- 1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM[1].
PD-1[1] [1]. Pottayil Govindan Nair Sasikumar, et al. 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators. WO2015033301A1. |
