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BTR-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BTR-1图片
CAS NO:18331-34-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)询价
5mg询价
10mg询价
50mg询价
100mg询价

BTR-1是一种活性抗癌剂,能够诱导细胞周期S期停滞,影响DNA复制。BTR-1可激活凋亡(apoptosis),导致细胞死亡。
Cas No.18331-34-5
Canonical SMILESS=C(N(CC)C/1=O)SC1=C/C2=CC=CC=C2
分子式C12H11NOS2
分子量249.35
溶解度DMSO : 25 mg/mL (100.26 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death[1]. Apoptosis[1]

BTR-1 (10, 50, 100, and 250 µM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 µM at 48 and 72 h, respectively[1]. Cell Viability Assay[1] Cell Line: T-cell leukemic cell lines

[1]. Moorthy BT, et al. Novel rhodanine derivatives induce growth inhibition followed by apoptosis. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6297-301.

 
 
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