N6-Cyclohexyladenosine (CHA) 是一种选择性 A1 受体激动剂 (EC50 = 8.2 nM)。
| Cas No. | 36396-99-3 |
| 别名 | A1受体促进剂,CHA,CHA |
| Canonical SMILES | OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NC4CCCCC4)O1)O)O |
| 分子式 | C16H23N5O4 |
| 分子量 | 349.38 |
| 溶解度 | DMSO : ≥ 100 mg/mL (286.22 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). IC50 value: 8.2 nM (EC50)Target: A1 receptorin vivo: N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor effects of lumbar sympathetic nerve stimulation in rats. [1]. Asghari AA, et al. Adenosine A1 receptor agonist, N6-cyclohexyladenosine, protects myelin and induces remyelination in an experimental model of rat optic chiasm demyelination; electrophysiological and histopathological studies. J Neurol Sci. 2013 Feb 15;3 |
