Alprenolol ((RS)-Alprenolol) ((RS)-Alprenolol ((RS)-Alprenolol); dl-Alprenolol ((RS)-Alprenolol)) 是一种具有口服活性的非选择性 β-adrenoceptor 拮抗剂和 5 的拮抗剂-HT1A 和 5-HT1B 受体。 Alprenolol ((RS)-Alprenolol) 用作抗高血压、抗心绞痛和抗心律失常药物。
| Cas No. | 13655-52-2 |
| 别名 | 阿普洛尔; (RS)-Alprenolol; dl-Alprenolol |
| Canonical SMILES | OC(COC1=CC=CC=C1CC=C)CNC(C)C |
| 分子式 | C15H23NO2 |
| 分子量 | 249.35 |
| 溶解度 | DMSO : ≥ 100 mg/mL (401.04 mM);Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Alprenolol is a non-selective beta blocker as well as 5-HT1A receptor antagonist.The reference for administration is 10 mg/kg. [1]. Schreiber R et al. Involvement of 5-HT1A receptors in the anxiolytic action of S 14671 in the pigeon conflict test. Pharmacol Biochem Behav. 1995 Jun-Jul;51(2-3):211-5. [2]. Millan MJ et al. Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther, 1994 Jan, 2 |
