CAS NO: | 85392-79-6 |
包装 | 价格(元) |
1mg | 询价 |
5mg | 询价 |
10mg | 询价 |
20mg | 询价 |
Cas No. | 85392-79-6 |
别名 | 吲达尼定 |
Canonical SMILES | CN1N=C2C=CC=C(NC3=NCCN3)C2=C1 |
分子式 | C11H13N5 |
分子量 | 215.25 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Indanidine is an alpha-adrenergic agonist. The selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo[1]. [1]. Van der Graaf PH, et al. Analysis of the action of idazoxan calls into question the reliability of the rat isolated small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity. Naunyn Schmiedebergs Arch Pharmacol. 1996 Aug-Sep;354(3):389-92. |
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