Rosmarinic acid racemate是Rosmarinic acid的外消旋体。Rosmarinic acid抑制MAO-A, MAO-B 和COMT酶,IC50分别为50.1, 184.6 和26.7 μM。
Cas No. | 537-15-5 |
别名 | 迷迭香素 |
Canonical SMILES | O=C(O)C(OC(/C=C/C1=CC=C(O)C(O)=C1)=O)CC2=CC=C(O)C(O)=C2 |
分子式 | C18H16O8 |
分子量 | 360.31 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Rosmarinic acid racemate is the racemate of Rosmarinic acid. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
Human Endogenous Metabolite [1]. Andrade JM, et al. Combining in vitro and in silico approaches to evaluate the multifunctional profile of rosmarinic acid from Blechnum brasiliense on targets related to neurodegeneration. Chem Biol Interact. 2016 Jul 25;254:135-45. |