Acetyldigitoxin (Digitoxin 3'''-Acetate) 是一种强心苷。
| Cas No. | 1111-39-3 |
| 别名 | 乙酰洋地黄毒甙; Digitoxin 3'''-Acetate |
| 分子式 | C43H66O14 |
| 分子量 | 807 |
| 溶解度 | Chloroform: Slightly Soluble,DMSO: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. This inhibition results in loss of the transmembrane Na+ gradient, which decreases activity of the Na+/Ca2+ exchanger, increasing intracellular calcium levels, inotropy, and cardiac force. Formulations containing acetyldigitoxin have been used for the treatment of heart failure and chronic atrial fibrillation. |
