Dihydrocapsaicin 是一种辣椒素，是一种有效的选择性 TRPV1（瞬时受体电位香草醛通道 1）激动剂。
| Cas No. | 19408-84-5 |
| 别名 | 二氢辣椒碱 |
| 化学名 | N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide |
| Canonical SMILES | CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC |
| 分子式 | C18H29NO3 |
| 分子量 | 307.43 |
| 溶解度 | DMF: 100 mg/ml,DMSO: 33 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 0.1 mg/ml |
| 储存条件 | Store at 2-8℃, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dihydrocapsaicin is a natural capsaicin, acts as a selective TRPV1 agonist, and also increases p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection[1][2]. References:
[1]. Gao F, et al. Impairment in function and expression of transient receptor potential vanilloid type 4 in Dahl salt-sensitive rats: significance and mechanism. Hypertension. 2010 Apr;55(4):1018-25.
[2]. Dihydrocapsaicin, et al. Dihydrocapsaicin (DHC) enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat. Brain Res. 2017 Sep 15;1671:18-25. |
