Effusol时可从Juncuseffuses中分离得到的一种酚类物质，对DPPH和ABTS自由基具有较强的清除活性，其IC50值分别为79μM和2.73μM。Effusol挽救皮质酮减弱的CA1LTP，保护海马功能对抗应激诱导的认知能力下降。
| Cas No. | 73166-28-6 |
| 别名 | 灯心草菲酚 |
| Canonical SMILES | OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C=C3C=C |
| 分子式 | C17H16O2 |
| 分子量 | 252.31 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1]. [1]. Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442(pISSN).
[2]. Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39(7):975-983. |
