Cinchonine ((8R,9S)-Cinchonine) 是一种存在于金鸡纳树皮中的天然化合物。 Cinchonine ((8R,9S)-Cinchonine) 在人肝癌细胞中激活内质网应激诱导的细胞凋亡。
| Cas No. | 118-10-5 |
| 别名 | 辛可宁; (8R,9S)-Cinchonine; LA40221 |
| Canonical SMILES | O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3 |
| 分子式 | C19H22N2O |
| 分子量 | 294.39 |
| 溶解度 | DMSO : 4.76 mg/mL (16.17 mM) |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cinchonine is a natural compound present in Cinchona bark. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]. [1]. Jin ZL, et al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050. |
