A fluorescent cholesterol analog
| Cas No. | 516-85-8 |
| 别名 | DHE, 9,11-dehydro Ergosterol |
| 化学名 | ergosta-5,7,9(11),22E-tetraen-3β-ol |
| Canonical SMILES | CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)C3=CC[C@@]21C |
| 分子式 | C28H42O |
| 分子量 | 394.6 |
| 溶解度 | 20mg/mL in ethanol, 0.1mg/mL in DMSO, 2mg/mL in DMF |
| 储存条件 | Store at -20℃,protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dehydroergosterol is a naturally occurring, fluorescent analog of cholesterol (ex/em = 324/375 nm) that mimics the properties of cholesterol in cell membranes.[1] It is readily bound by cholesterol-binding proteins and has been used for real-time probing of the sterol environment and to elucidate intracellular sterol trafficking in living organisms.[1] Reference:
[1]. McIntosh, A.L., Atshaves, B.P., Huang, H., et al. Fluorescence techniques using dehydroergosterol to study cholesterol trafficking. Lipids 43(12), 1185-1208 (2008). |
