| CAS NO: | 92169-45-4 |
| Cas No. | 92169-45-4 |
| 别名 | Neuromedin N (rat, mouse, porcine, canine) |
| 分子式 | C38H63N7O8 |
| 分子量 | 745.95 |
| 溶解度 | Water: 50 mg/mL (67.03 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Dopamine D2 receptor[1]. Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin[2]. [1]. Li XM, et al. Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neurosci Lett. 1993 Jun 11;155(2):121-4. [2]. Checler F, et al. Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur J Pharmacol. 1986 Jul 31;126(3):239-44. |
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