| CAS NO: | 57-13-6 |
| 包装: | 1kg |
| 市场价: | 1160元 |
| Physical Appearance | A solid |
| Storage | Store at RT |
| M.Wt | 60.06 |
| Cas No. | 57-13-6 |
| Formula | CH4N2O |
| Solubility | ≥19.27 mg/mL in EtOH with ultrasonic; ≥55.7 mg/mL in H2O; ≥6 mg/mL in DMSO |
| Chemical Name | urea |
| Canonical SMILES | O=C(N)N |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Urea is an organic compound generated by the urea cycle enzymes, which is then eliminated through fluids, especially urine. Blood urea nitrogen has been utilized to evaluate renal function for decades. In addition, urea has been used clinically for a variety of dermatological diseases over a century. Urea is a potent emollient and keratolytic agent, making it an effective topical monotherapy for conditions such as dry and scaly skin. Due to its high solubility in aqueous solution, urea further extends its applications in laboratory, serving as a powerful protein denaturant for assessing protein stability, the effects of mutations on stability, and protein unfolding.
References:
1. Wang H, Ran J, Jiang T. Urea. Subcellular Biochemistry, 2014, 73: 7-29.
2. Pan M, Heinecke G, Bernardo S, et al. Urea: a comprehensive review of the clinical literature. Dermatology Online Journal, 2013, 19(11): 20392.
3. Bennion BJ, Daggett V. The molecular basis for the chemical denaturation of proteins by urea. Proceedings of the National Academy of Sciences of the United States of America, 2003, 100(9): 5142-5147.
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