CP 100356 hydrochloride 是一种具有口服活性的 MDR1 (P-gp)/BCRP 双重抑制剂，抑制 MDR1 介导的 Calcein-AM 转运和 BCRP 介导的哌唑嗪转运的 IC50 分别为 0.5 和 1.5 μM。
| Cas No. | 142715-48-8 |
| 化学名 | 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-(3,4-dimethoxyphenethyl)-6,7-dimethoxyquinazolin-2-amine hydrochloride |
| Canonical SMILES | COC(C=C1CCN(C(C2=C3)=NC(NCCC(C=C4OC)=CC=C4OC)=NC2=CC(OC)=C3OC)CC1=C5)=C5OC.Cl |
| 分子式 | C31H36N4O6.HCl |
| 分子量 | 597.1 |
| 溶解度 | <11.94mg/ml in DMSO |
| 储存条件 | Desiccate at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
