Propargyl-PEG4-O-C1-NHS ester (compound 8) 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG4-O-C1-NHS ester可用于合成一系列 PROTAC 分子。
Cas No. | 1161883-51-7 |
分子式 | C17H25NO9 |
分子量 | 387.38 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |