| 别名 | ac4CTP sodium |
| Canonical SMILES | O[C@@H]([C@H]([C@H](N1C(N=C(C=C1)NC(C)=O)=O)O2)O)[C@H]2COP([O-])(OP(OP([O-])([O-])=O)([O-])=O)=O.[4 Na+] |
| 分子式 | C11H14N3Na4O15P3 |
| 分子量 | 613.12 |
| 溶解度 | Water: ≥ 250 mg/mL (407.75 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N4-Acetylcytidine triphosphate sodium is a endogenous nucleoside metabolite from the degradation of tRNA, primes and activates NLRP3 inflammation by inducing HMGB1 expression[1]. NLRP3 Human Endogenous Metabolite N4-Acetylcytidine (0.3? mM or 1.0? mM) upregulates NF-κB and NLRP3 expression BV2 microglia, and this calls for HMGB1 expression and release[1]. [1]. Duan J, et al. N4-acetylcytidine is required for sustained NLRP3 inflammasome activation via HMGB1 pathway in microglia. Cell Signal. 2019 Jun;58:44-52. |
| 维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024 |