化学性质
Physical Appearance | A crystalline solid |
Storage | Store at -20°C |
M.Wt | 698.54 |
Cas No. | 132172-61-3 |
Formula | C42H80ClNO4 |
Solubility | insoluble in H2O; ≥19.33 mg/mL in DMSO; ≥9.76 mg/mL in EtOH |
Chemical Name | N,N,N-trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride |
Canonical SMILES | CCCCCCCC/C=C\CCCCCCCC(OC(COC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)C)=O.[Cl-] |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
1,2-Dioleoyl-3-trimethylammoniumpropane (DOTAP) is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in the composition of small unilamellar liposomes formulated as a gene delivery vectors for gene therapy[1].
Reference:
[1]. Xiong F, Mi Z, and Gu N. Cationic liposomes as gene delivery system: Transfection efficiency and new application. Pharmazie, 2011, 66(3): 158-164.